MolNFT v1 · #316250 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 1 homolog a (O48844)
O48844: “AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 1 homolog a (O48844)”. 11 pockets (best druggability 0.85). MolNFT v1 #316250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O48844
- Type
- protein
- Length
- 1,004 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8881898ab018738C7Ce955f1E677a924330a5A7E
- Molecule
- 26S proteasome non-ATPase regulatory subunit 1 homolog a
- UniProt
- O48844
- Pockets
- 11 · best druggability 0.85
Structure
1 distinct chain · 57% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome non-ATPase regulatory subunit 1 homolog a | protein | 1004 | 57% helix, 4% strand | O48844 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 316 | 0.85 | 0.95 | 48 | empty |
| 2 | 633 | 0.76 | 0.82 | 72 | empty |
| 3 | 182 | 0.60 | 0.82 | 31 | empty |
| 4 | 227 | 0.53 | 0.77 | 31 | empty |
| 5 | 67 | 0.49 | 0.84 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O48844
- Elsewhere: UniProt O48844 · AlphaFold DB O48844
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