MolNFT v1 · #312139 · protein
AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-5 (P28066)
P28066: “AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-5 (P28066)”. 2 pockets (best druggability 0.29). MolNFT v1 #312139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P28066
- Type
- protein
- Length
- 241 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Proteasome subunit alpha type-5
- UniProt
- P28066
- Pockets
- 2 · best druggability 0.29
Structure
1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteasome subunit alpha type-5 | protein | 241 | 36% helix, 23% strand | P28066 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.29 | 0.75 | 14 | empty |
| 2 | 55 | 0.27 | 0.73 | 16 | empty |
Compared structures
- 9E8Q · Nub1/Fat10-processing human 26S proteasome with Rpt2 at top of spiral staircase · an experimental structure of the same protein · chain A against K, TM-score 0.96
- 7W3B · Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 · an experimental structure of the same protein · chain A against K, TM-score 0.96
- 7LXV · Structure of human 20S proteasome with bound mpi-5 · an experimental structure of the same protein · chain A against D, TM-score 0.95
- 8UD9 · Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304 · an experimental structure of the same protein · chain A against E, TM-score 0.95
- 7NHT · AKIRIN2 bound human proteasome · an experimental structure of the same protein · chain A against D, TM-score 0.95
- 7NHT · Akirin2 bound human proteasome · an experimental structure of the same protein · chain A against D, TM-score 0.95
- 6KWY · Human PA200-20S complex · an experimental structure of the same protein · chain A against R, TM-score 0.94
- 6RGQ · Human 20S proteasome · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 8CVR · Human 20S proteasome with MG-132 · an experimental structure of the same protein · chain A against E, TM-score 0.94
- 5GJQ · Structure of the human 26S proteasome bound to USP14-ubal · an experimental structure of the same protein · chain A against F, TM-score 0.94
- 5GJR · An atomic structure of the human 26S proteasome · an experimental structure of the same protein · chain A against F, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28066
- Elsewhere: UniProt P28066 · AlphaFold DB P28066
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.