MolNFT v1 · #312085 · protein
AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-2 (P49722)
P49722: “AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-2 (P49722)”. 2 pockets (best druggability 0.43). MolNFT v1 #312085 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49722
- Type
- protein
- Length
- 234 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Proteasome subunit alpha type-2
- UniProt
- P49722
- Pockets
- 2 · best druggability 0.43
Structure
1 distinct chain · 39% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteasome subunit alpha type-2 | protein | 234 | 39% helix, 24% strand | P49722 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.43 | 0.80 | 15 | empty |
| 2 | 93 | 0.36 | 0.75 | 21 | empty |
Compared structures
- 3UNB · Mouse constitutive 20S proteasome in complex with PR-957 · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 3UNB · Mouse constitutive 20S proteasome in complex with pr-957 · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 3UNE · Mouse constitutive 20S proteasome · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 3UNE · Mouse constitutive 20S proteasome · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 3UNH · Mouse 20S immunoproteasome · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 3UNH · Mouse 20S immunoproteasome · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 3UNF · Mouse 20S immunoproteasome in complex with pr-957 · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 3UNF · Mouse 20S immunoproteasome in complex with PR-957 · an experimental structure of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49722
- Elsewhere: UniProt P49722 · AlphaFold DB P49722
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