AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-1 (P21243)

Structure

1 distinct chain · 38% helix, 22% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 4LTC · Crystal structure of yeast 20S proteasome in complex with e carmaphycin analogue 6 · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4HRC · Crystal structure of yeast 20S proteasome in complex with epoxyketone carmaphycin… · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4HNP · Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin… · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4J70 · Yeast 20S proteasome in complex with the belactosin derivative 3e · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4FZC · 20S yeast proteasome in complex with cepafungin I · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4HRD · Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin… · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 3OKJ · Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome… · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 3E47 · Crystal Structure of the Yeast 20S Proteasome in Complex with Homobelactosin C · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 3TDD · Crystal structure of yeast CP in complex with Belactosin C · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 3UN4 · Yeast 20S proteasome in complex with PR-957 (morpholine) · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4FZG · 20S yeast proteasome in complex with glidobactin · an experimental structure of the same protein · chain A against G, TM-score 0.95
• 4JSQ · Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4e · an experimental structure of the same protein · chain A against G, TM-score 0.95

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P21243
• Elsewhere: UniProt P21243 · AlphaFold DB P21243