MolNFT v1 · #311819 · protein
AlphaFold monomer V2.0 prediction for extracellular serine protease (P09489)
P09489: “AlphaFold monomer V2.0 prediction for extracellular serine protease (P09489)”. 9 pockets (best druggability 0.78). MolNFT v1 #311819 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P09489
- Type
- protein
- Length
- 1,045 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Extracellular serine protease
- UniProt
- P09489
- Pockets
- 9 · best druggability 0.78
Structure
1 distinct chain · 19% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Extracellular serine protease | protein | 1045 | 19% helix, 39% strand | P09489 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.78 | 0.98 | 36 | empty |
| 2 | 114 | 0.75 | 0.95 | 33 | empty |
| 3 | 124 | 0.56 | 0.83 | 25 | empty |
| 4 | 79 | 0.47 | 0.83 | 20 | empty |
| 5 | 125 | 0.39 | 0.75 | 20 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 8E7F · Crystal structure of the autotransporter Ssp from Serratia marcescens. · an experimental structure of the same protein · chain A against A, TM-score 0.58
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09489
- Elsewhere: UniProt P09489 · AlphaFold DB P09489
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