MolNFT v1 · #311622 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 8 (P46470)
P46470: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 8 (P46470)”. 2 pockets (best druggability 0.57). MolNFT v1 #311622 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P46470
- Type
- protein
- Length
- 461 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x87dF0a0F837fB48431e1E24dE4e437FC0A6743Aa
- Molecule
- 26S proteasome regulatory subunit 8
- UniProt
- P46470
- Pockets
- 2 · best druggability 0.57
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome regulatory subunit 8 | protein | 461 | 44% helix, 14% strand | P46470 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 193 | 0.57 | 0.80 | 37 | empty |
| 2 | 76 | 0.30 | 0.73 | 11 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46470
- Elsewhere: UniProt P46470 · AlphaFold DB P46470
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