MolNFT v1 · #311246 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing-splicing factor 8B (Q9T0I6)
Q9T0I6: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing-splicing factor 8B (Q9T0I6)”. 20 pockets (best druggability 0.82). MolNFT v1 #311246 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9T0I6
- Type
- protein
- Length
- 2,359 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0B68cA60C95B982f45BEE070Fa9f83ABE55bc841
- Molecule
- Pre-mRNA-processing-splicing factor 8B
- UniProt
- Q9T0I6
- Pockets
- 20 · best druggability 0.82
Structure
1 distinct chain · 43% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing-splicing factor 8B | protein | 2359 | 43% helix, 13% strand | Q9T0I6 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 890 | 0.82 | 0.84 | 98 | empty |
| 2 | 881 | 0.79 | 0.82 | 88 | empty |
| 3 | 955 | 0.77 | 0.79 | 84 | empty |
| 4 | 654 | 0.68 | 0.76 | 68 | empty |
| 5 | 499 | 0.63 | 0.76 | 49 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9T0I6
- Elsewhere: UniProt Q9T0I6 · AlphaFold DB Q9T0I6
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