MolNFT v1 · #311226 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing ATP- dependent RNA helicase PRP5 (A5E058)
A5E058 · Pre-mRNA-processing ATP-dependent RNA helicase PRP5: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing ATP- dependent RNA helicase PRP5 (A5E058)”. 8 pockets (best druggability 0.71). MolNFT v1 #311226 on GenesisL1: 3D…
- Accession
- A5E058
- Type
- protein
- Length
- 994 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xDa30399E955a842042B4DfB2a86B9Aff5E5aB0e8
- Molecule
- Pre-mRNA-processing ATP-dependent RNA helicase PRP5
- UniProt
- A5E058
- Pockets
- 8 · best druggability 0.71
Structure
1 distinct chain · 41% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing ATP-dependent RNA helicase PRP5 | protein | 994 | 41% helix, 10% strand | A5E058 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 550 | 0.71 | 0.80 | 60 | empty |
| 2 | 786 | 0.68 | 0.75 | 65 | empty |
| 3 | 315 | 0.54 | 0.74 | 36 | empty |
| 4 | 213 | 0.44 | 0.73 | 22 | empty |
| 5 | 105 | 0.35 | 0.74 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5E058
- Elsewhere: UniProt A5E058 · AlphaFold DB A5E058
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