MolNFT v1 · #311196 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PRPF4B (Q54WE5)
Q54WE5: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PRPF4B (Q54WE5)”. 7 pockets (best druggability 0.72). MolNFT v1 #311196 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q54WE5
- Type
- protein
- Length
- 811 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x71112d4fF7ebb3b617963c05f052289e073082FD
- Molecule
- SERINE/THREONINE-protein kinase PRPF4B
- UniProt
- Q54WE5
- Pockets
- 7 · best druggability 0.72
Structure
1 distinct chain · 30% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PRPF4B | protein | 811 | 30% helix, 8% strand | Q54WE5 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 581 | 0.72 | 0.80 | 50 | empty |
| 2 | 253 | 0.59 | 0.79 | 32 | empty |
| 3 | 242 | 0.53 | 0.76 | 35 | empty |
| 4 | 81 | 0.53 | 0.85 | 13 | empty |
| 5 | 56 | 0.38 | 0.80 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q54WE5
- Elsewhere: UniProt Q54WE5 · AlphaFold DB Q54WE5
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