MolNFT v1 · #311193 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP46 (Q6C709)
Q6C709: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP46 (Q6C709)”. 6 pockets (best druggability 0.76). MolNFT v1 #311193 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6C709
- Type
- protein
- Length
- 441 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7B796178fC6Ce532fb47128c798044ffa999dCA5
- Molecule
- Pre-mRNA-splicing factor PRP46
- UniProt
- Q6C709
- Pockets
- 6 · best druggability 0.76
Structure
1 distinct chain · 7% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor PRP46 | protein | 441 | 7% helix, 38% strand | Q6C709 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 854 | 0.76 | 0.80 | 70 | empty |
| 2 | 188 | 0.57 | 0.81 | 29 | empty |
| 3 | 171 | 0.51 | 0.78 | 23 | empty |
| 4 | 214 | 0.49 | 0.75 | 23 | empty |
| 5 | 70 | 0.40 | 0.80 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6C709
- Elsewhere: UniProt Q6C709 · AlphaFold DB Q6C709
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