MolNFT v1 · #311168 · protein
AlphaFold monomer V2.0 prediction for probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3 (O22899)
O22899: “AlphaFold monomer V2.0 prediction for probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3…”. 8 pockets (best druggability 0.83). MolNFT v1 #311168 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O22899
- Type
- protein
- Length
- 729 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd6ce0c7C49c82dFd45bc32bF85412d99a1588283
- Molecule
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3
- UniProt
- O22899
- Pockets
- 8 · best druggability 0.83
Structure
1 distinct chain · 42% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH3 | protein | 729 | 42% helix, 18% strand | O22899 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 890 | 0.83 | 0.85 | 104 | empty |
| 2 | 369 | 0.68 | 0.81 | 46 | empty |
| 3 | 70 | 0.57 | 0.89 | 20 | empty |
| 4 | 94 | 0.44 | 0.79 | 21 | empty |
| 5 | 134 | 0.41 | 0.75 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O22899
- Elsewhere: UniProt O22899 · AlphaFold DB O22899
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