MolNFT v1 · #311130 · protein

AlphaFold monomer V2.0 prediction for phenoloxidase subunit 2 (Q25519)

Q25519: “AlphaFold monomer V2.0 prediction for phenoloxidase subunit 2 (Q25519)”. 11 pockets (best druggability 0.64). MolNFT v1 #311130 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q25519
Type: protein
Length: 695 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule: Phenoloxidase subunit 2
UniProt: Q25519
Pockets: 11 · best druggability 0.64

Structure

1 distinct chain · 36% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phenoloxidase subunit 2	protein	695	36% helix, 19% strand	Q25519

Pockets

11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.64	0.91	24	empty
2	315	0.59	0.78	34	empty
3	154	0.55	0.81	34	empty
4	142	0.50	0.79	26	empty
5	127	0.49	0.79	15	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3HHS · Crystal structure of manduca sexta prophenoloxidase · an experimental structure of the same protein · chain A against A, TM-score 0.96
3HHS · Crystal Structure of Manduca sexta prophenoloxidase · an experimental structure of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q25519
Elsewhere: UniProt Q25519 · AlphaFold DB Q25519

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