GL1X · GenesisL1 explorer

MolNFT v1 · #311117 · protein

AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (Q0UWC8)

Q0UWC8: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (Q0UWC8)”. 5 pockets (best druggability 0.68). MolNFT v1 #311117 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q0UWC8
Type
protein
Length
746 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28
UniProt
Q0UWC8
Pockets
5 · best druggability 0.68

Structure

1 distinct chain · 43% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-splicing ATP-dependent RNA helicase PRP28protein74643% helix, 9% strandQ0UWC8

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13940.680.8149empty
22140.580.8032empty
31450.470.7721empty
4950.350.7420empty
5580.350.7815empty

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