MolNFT v1 · #311089 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP1 (Q12381)
Q12381: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP1 (Q12381)”. 5 pockets (best druggability 0.75). MolNFT v1 #311089 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q12381
- Type
- protein
- Length
- 906 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3298b100681D3A2372Bba3b2f282750dD71629B9
- Molecule
- Pre-mRNA-splicing factor PRP1
- UniProt
- Q12381
- Pockets
- 5 · best druggability 0.75
Structure
1 distinct chain · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor PRP1 | protein | 906 | 68% helix, 0% strand | Q12381 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1157 | 0.75 | 0.78 | 71 | empty |
| 2 | 80 | 0.53 | 0.85 | 17 | empty |
| 3 | 92 | 0.43 | 0.79 | 20 | empty |
| 4 | 58 | 0.39 | 0.80 | 13 | empty |
| 5 | 81 | 0.37 | 0.76 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12381
- Elsewhere: UniProt Q12381 · AlphaFold DB Q12381
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