MolNFT v1 · #311086 · protein

AlphaFold monomer V2.0 prediction for phenoloxidase subunit 1 (O44249)

O44249: “AlphaFold monomer V2.0 prediction for phenoloxidase subunit 1 (O44249)”. 10 pockets (best druggability 0.73). MolNFT v1 #311086 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O44249
Type: protein
Length: 685 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x92aBF7FbE5b4A62e611253Dd271820D19bCD91cc
Molecule: Phenoloxidase subunit 1
UniProt: O44249
Pockets: 10 · best druggability 0.73

Structure

1 distinct chain · 38% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phenoloxidase subunit 1	protein	685	38% helix, 19% strand	O44249

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.73	0.99	19	empty
2	127	0.62	0.86	26	empty
3	277	0.56	0.77	35	empty
4	144	0.51	0.79	23	empty
5	59	0.48	0.85	22	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3HHS · Crystal Structure of Manduca sexta prophenoloxidase · an experimental structure of the same protein · chain A against B, TM-score 0.95
3HHS · Crystal structure of manduca sexta prophenoloxidase · an experimental structure of the same protein · chain A against B, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O44249
Elsewhere: UniProt O44249 · AlphaFold DB O44249

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