MolNFT v1 · #311049 · protein
AlphaFold monomer V2.0 prediction for vitamin K-dependent protein Z (P22891)
P22891: “AlphaFold monomer V2.0 prediction for vitamin K-dependent protein Z (P22891)”. 6 pockets (best druggability 0.57). MolNFT v1 #311049 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22891
- Type
- protein
- Length
- 400 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- Vitamin K-dependent protein Z
- UniProt
- P22891
- Pockets
- 6 · best druggability 0.57
Structure
1 distinct chain · 21% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vitamin K-dependent protein Z | protein | 400 | 21% helix, 29% strand | P22891 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.57 | 0.84 | 19 | empty |
| 2 | 128 | 0.48 | 0.79 | 23 | empty |
| 3 | 72 | 0.43 | 0.81 | 16 | empty |
| 4 | 98 | 0.42 | 0.78 | 17 | empty |
| 5 | 109 | 0.40 | 0.76 | 24 | empty |
Modifications
Observed in the structure: 11 disulfide (disulfide).
Compared structures
- 3H5C · X-Ray Structure of Protein Z-Protein Z Inhibitor Complex · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 3H5C · X-ray structure of protein Z-protein Z inhibitor complex · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 3F1S · Crystal structure of protein Z complexed with protein Z-dependent inhibitor · an experimental structure of the same protein · chain A against B, TM-score 0.64
- 3F1S · Crystal structure of Protein Z complexed with protein Z-dependent inhibitor · an experimental structure of the same protein · chain A against B, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22891
- Elsewhere: UniProt P22891 · AlphaFold DB P22891
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