MolNFT v1 · #310701 · protein
AlphaFold monomer V2.0 prediction for proline dehydrogenase 1, mitochondrial (O43272)
O43272: “AlphaFold monomer V2.0 prediction for proline dehydrogenase 1, mitochondrial (O43272)”. 7 pockets (best druggability 0.78). MolNFT v1 #310701 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43272
- Type
- protein
- Length
- 600 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7322182A904Ab8270621E3B35dc80C787052A76f
- Molecule
- Proline dehydrogenase 1, mitochondrial
- UniProt
- O43272
- Pockets
- 7 · best druggability 0.78
Structure
1 distinct chain · 52% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proline dehydrogenase 1, mitochondrial | protein | 600 | 52% helix, 10% strand | O43272 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 609 | 0.78 | 0.84 | 64 | empty |
| 2 | 490 | 0.77 | 0.85 | 56 | empty |
| 3 | 234 | 0.58 | 0.79 | 25 | empty |
| 4 | 122 | 0.57 | 0.83 | 17 | empty |
| 5 | 134 | 0.48 | 0.79 | 29 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43272
- Elsewhere: UniProt O43272 · AlphaFold DB O43272
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