MolNFT v1 · #308831 · protein
AlphaFold monomer V2.0 prediction for alpha-lytic protease (P00778)
P00778: “AlphaFold monomer V2.0 prediction for alpha-lytic protease (P00778)”. 1 pocket (best druggability 0.34). MolNFT v1 #308831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P00778
- Type
- protein
- Length
- 397 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Alpha-lytic protease
- UniProt
- P00778
- Pockets
- 1 · best druggability 0.34
Structure
1 distinct chain · 20% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-lytic protease | protein | 397 | 20% helix, 38% strand | P00778 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.34 | 0.74 | 21 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2ALP · Refined structure of alpha-lytic protease at 1.7 ångströms resolution. analysis of… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 2ALP · Refined structure of alpha-lytic protease at 1.7 ångströms resolution. analysis of… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3M7T · Crystal Structure of Alpha-Lytic Protease SB2+3 E8A/R105S Mutant · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3M7T · Crystal structure of alpha-lytic protease SB2+3 E8A/R105S mutant · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3URD · T181A mutant of alpha-lytic protease · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3URD · T181A mutant of alpha-Lytic Protease · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3URC · T181G mutant of alpha-lytic protease · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 3URC · T181G mutant of alpha-Lytic Protease · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 1P01 · Serine protease mechanism. structure of an inhibitory complex of alpha-lytic protease and… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 1P01 · Serine protease mechanism. structure of an inhibitory complex oF ALPHA-LYTIC Protease and… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 1P02 · Structure analysis of specificity. alpha-lytic protease complexes with analogues of… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 1P02 · Structure analysis of specificity. alpha-lytic protease complexes with analogues of… · an experimental structure of the same protein · chain A against A, TM-score 0.50
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00778
- Elsewhere: UniProt P00778 · AlphaFold DB P00778
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