MolNFT v1 · #308691 · protein
AlphaFold monomer V2.0 prediction for major prion protein (P67994)
P67994: “AlphaFold monomer V2.0 prediction for major prion protein (P67994)”. 2 pockets (best druggability 0.32). MolNFT v1 #308691 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P67994
- Type
- protein
- Length
- 253 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- Major prion protein
- UniProt
- P67994
- Pockets
- 2 · best druggability 0.32
Structure
1 distinct chain · 42% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major prion protein | protein | 253 | 42% helix, 2% strand | P67994 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.32 | 0.73 | 18 | empty |
| 2 | 63 | 0.29 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P67994
- Elsewhere: UniProt P67994 · AlphaFold DB P67994
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