MolNFT v1 · #308114 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 40 homolog a (O75400)
O75400: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 40 homolog a (O75400)”. 2 pockets (best druggability 0.47). MolNFT v1 #308114 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O75400
- Type
- protein
- Length
- 957 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2358fDf347F514B5e6fFcFa89F8c28fA3A0E58EF
- Molecule
- Pre-mRNA-processing factor 40 homolog a
- UniProt
- O75400
- Pockets
- 2 · best druggability 0.47
Structure
1 distinct chain · 39% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing factor 40 homolog a | protein | 957 | 39% helix, 3% strand | O75400 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.47 | 0.79 | 14 | empty |
| 2 | 138 | 0.41 | 0.74 | 15 | empty |
Compared structures
- 2CQN · Solution structure of the ff domain of human formin-binding protein 3 · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2CQN · Solution structure of the FF domain of human Formin-binding protein 3 · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2KZG · A transient and low populated protein folding intermediate at atomic resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2KZG · A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2L9V · NMR structure of the FF domain L24A mutant's folding transition state · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2L9V · NMR structure of the ff domain L24A MUTANT'S folding transition state · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2LKS · Ff11-60 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2LKS · FF11-60 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2L5F · Solution structure of the tandem WW domains from HYPA/FBP11 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2L5F · Solution structure of the tandem ww domains from HYPA/FBP11 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2DYF · Solution structure of the first WW domain of FBP11 / HYPA (FBP11 WW1) complexed with a PL… · an experimental structure of the same protein · chain A against A, TM-score 0.03
- 2DYF · Solution structure of the first ww domain of FBP11 / hypa (FBP11 WW1) complexed with a pl… · an experimental structure of the same protein · chain A against A, TM-score 0.03
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75400
- Elsewhere: UniProt O75400 · AlphaFold DB O75400
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