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MolNFT v1 · #308114 · protein

AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 40 homolog a (O75400)

O75400: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 40 homolog a (O75400)”. 2 pockets (best druggability 0.47). MolNFT v1 #308114 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O75400
Type
protein
Length
957 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x2358fDf347F514B5e6fFcFa89F8c28fA3A0E58EF
Molecule
Pre-mRNA-processing factor 40 homolog a
UniProt
O75400
Pockets
2 · best druggability 0.47

Structure

1 distinct chain · 39% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-processing factor 40 homolog aprotein95739% helix, 3% strandO75400

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.470.7914empty
21380.410.7415empty

Compared structures

  • 2CQN · Solution structure of the ff domain of human formin-binding protein 3 · an experimental structure of the same protein · chain A against A, TM-score 0.07
  • 2CQN · Solution structure of the FF domain of human Formin-binding protein 3 · an experimental structure of the same protein · chain A against A, TM-score 0.07
  • 2KZG · A transient and low populated protein folding intermediate at atomic resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2KZG · A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2L9V · NMR structure of the FF domain L24A mutant's folding transition state · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2L9V · NMR structure of the ff domain L24A MUTANT'S folding transition state · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2LKS · Ff11-60 · an experimental structure of the same protein · chain A against A, TM-score 0.04
  • 2LKS · FF11-60 · an experimental structure of the same protein · chain A against A, TM-score 0.04
  • 2L5F · Solution structure of the tandem WW domains from HYPA/FBP11 · an experimental structure of the same protein · chain A against A, TM-score 0.04
  • 2L5F · Solution structure of the tandem ww domains from HYPA/FBP11 · an experimental structure of the same protein · chain A against A, TM-score 0.04
  • 2DYF · Solution structure of the first WW domain of FBP11 / HYPA (FBP11 WW1) complexed with a PL… · an experimental structure of the same protein · chain A against A, TM-score 0.03
  • 2DYF · Solution structure of the first ww domain of FBP11 / hypa (FBP11 WW1) complexed with a pl… · an experimental structure of the same protein · chain A against A, TM-score 0.03

Analyse

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