MolNFT v1 · #307721 · protein

AlphaFold monomer V2.0 prediction for exopolyphosphatase (P0AFL8)

P0AFL8: “AlphaFold monomer V2.0 prediction for exopolyphosphatase (P0AFL8)”. 6 pockets (best druggability 0.69). MolNFT v1 #307721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P0AFL8
Type: protein
Length: 513 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaC514600d460a5a28A3caA451c2Dc7caE527a52C
Molecule: Exopolyphosphatase
UniProt: P0AFL8
Pockets: 6 · best druggability 0.69

Structure

1 distinct chain · 50% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exopolyphosphatase	protein	513	50% helix, 17% strand	P0AFL8

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	251	0.69	0.85	43	empty
2	345	0.66	0.80	41	empty
3	183	0.52	0.78	32	empty
4	116	0.49	0.80	19	empty
5	221	0.48	0.75	34	empty

Compared structures

2FLO · Crystal structure of exopolyphosphatase (PPX) from E. coli O157:H7 · an experimental structure of the same protein · chain A against A, TM-score 0.96
2FLO · Crystal structure of exopolyphosphatase (ppx) from E. COLI O157:H7 · an experimental structure of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AFL8
Elsewhere: UniProt P0AFL8 · AlphaFold DB P0AFL8

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