MolNFT v1 · #305857 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase PP2A-5 catalytic subunit (O04951)
O04951: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase PP2A-5 catalytic subunit (O04951)”. 3 pockets (best druggability 0.54). MolNFT v1 #305857 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O04951
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xCbAB44eAF7010f6D58F509F23fD04415aAbC4Fba
- Molecule
- SERINE/THREONINE-protein phosphatase PP2A-5 catalytic subunit
- UniProt
- O04951
- Pockets
- 3 · best druggability 0.54
Structure
1 distinct chain · 36% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein phosphatase PP2A-5 catalytic subunit | protein | 307 | 36% helix, 18% strand | O04951 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.54 | 0.83 | 19 | empty |
| 2 | 93 | 0.36 | 0.75 | 21 | empty |
| 3 | 58 | 0.29 | 0.74 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O04951
- Elsewhere: UniProt O04951 · AlphaFold DB O04951
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