MolNFT v1 · #305138 · protein
AlphaFold monomer V2.0 prediction for ribonucleases P/MRP protein subunit POP1 (P41812)
P41812: “AlphaFold monomer V2.0 prediction for ribonucleases P/MRP protein subunit POP1 (P41812)”. 12 pockets (best druggability 0.81). MolNFT v1 #305138 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P41812
- Type
- protein
- Length
- 875 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe35916812bf8eD8a10C099573e7bab220EE9feB9
- Molecule
- Ribonucleases P/MRP protein subunit POP1
- UniProt
- P41812
- Pockets
- 12 · best druggability 0.81
Structure
1 distinct chain · 38% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonucleases P/MRP protein subunit POP1 | protein | 875 | 38% helix, 17% strand | P41812 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 176 | 0.81 | 0.96 | 25 | empty |
| 2 | 558 | 0.73 | 0.81 | 58 | empty |
| 3 | 721 | 0.72 | 0.78 | 69 | empty |
| 4 | 401 | 0.65 | 0.79 | 42 | empty |
| 5 | 433 | 0.63 | 0.77 | 42 | empty |
Compared structures
- 6AGB · Cryo-EM structure of yeast Ribonuclease P · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 6AGB · Cryo-EM structure of yeast ribonuclease P · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 6AH3 · Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 6AH3 · Cryo-EM structure of yeast ribonuclease P with pre-tRNA substrate · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 6W6V · Structure of yeast RNase MRP holoenzyme · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 6W6V · Structure of yeast RNase mrp holoenzyme · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 7C79 · Cryo-EM structure of yeast ribonuclease mrp · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 7C79 · Cryo-EM structure of yeast Ribonuclease MRP · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 7C7A · Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1 · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 7C7A · Cryo-EM structure of yeast ribonuclease mrp with substrate ITS1 · an experimental structure of the same protein · chain A against B, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41812
- Elsewhere: UniProt P41812 · AlphaFold DB P41812
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