MolNFT v1 · #303918 · protein
AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (A4Q998)
A4Q998: “AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (A4Q998)”. 3 pockets (best druggability 0.61). MolNFT v1 #303918 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A4Q998
- Type
- protein
- Length
- 353 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Purine nucleoside phosphorylase
- UniProt
- A4Q998
- Pockets
- 3 · best druggability 0.61
Structure
1 distinct chain · 30% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Purine nucleoside phosphorylase | protein | 353 | 30% helix, 19% strand | A4Q998 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 139 | 0.61 | 0.85 | 26 | empty |
| 2 | 132 | 0.51 | 0.80 | 25 | empty |
| 3 | 64 | 0.29 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2P4S · Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 2P4S · Structure of purine nucleoside phosphorylase from anopheles gambiae in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4Q998
- Elsewhere: UniProt A4Q998 · AlphaFold DB A4Q998
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