MolNFT v1 · #303769 · protein
AlphaFold monomer V2.0 prediction for nicotinate phosphoribosyltransferase (P22253)
P22253: “AlphaFold monomer V2.0 prediction for nicotinate phosphoribosyltransferase (P22253)”. 3 pockets (best druggability 0.78). MolNFT v1 #303769 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22253
- Type
- protein
- Length
- 400 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x93c9c10cD9Ce1353A32B4e012FD69d78688DF18A
- Molecule
- Nicotinate phosphoribosyltransferase
- UniProt
- P22253
- Pockets
- 3 · best druggability 0.78
Structure
1 distinct chain · 47% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nicotinate phosphoribosyltransferase | protein | 400 | 47% helix, 15% strand | P22253 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 481 | 0.78 | 0.86 | 77 | empty |
| 2 | 50 | 0.28 | 0.75 | 12 | empty |
| 3 | 54 | 0.25 | 0.73 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22253
- Elsewhere: UniProt P22253 · AlphaFold DB P22253
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