MolNFT v1 · #303168 · protein

AlphaFold monomer V2.0 prediction for ATPase 2, plasma membrane-type (P19456)

P19456: “AlphaFold monomer V2.0 prediction for ATPase 2, plasma membrane-type (P19456)”. 12 pockets (best druggability 0.79). MolNFT v1 #303168 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P19456
Type: protein
Length: 948 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule: ATPase 2, plasma membrane-type
UniProt: P19456
Pockets: 12 · best druggability 0.79

Structure

1 distinct chain · 55% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATPase 2, plasma membrane-type	protein	948	55% helix, 13% strand	P19456

Pockets

12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1059	0.79	0.80	78	empty
2	127	0.58	0.84	21	empty
3	388	0.58	0.75	41	empty
4	281	0.53	0.75	36	empty
5	151	0.52	0.80	27	empty

Compared structures

5KSD · Crystal structure of a plasma membrane proton pump · an experimental structure of the same protein · chain A against A, TM-score 0.87
5KSD · Crystal Structure of a Plasma Membrane Proton Pump · an experimental structure of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19456
Elsewhere: UniProt P19456 · AlphaFold DB P19456

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