MolNFT v1 · #303164 · protein
AlphaFold monomer V2.0 prediction for plasma membrane ATPase 1 (P22180)
P22180: “AlphaFold monomer V2.0 prediction for plasma membrane ATPase 1 (P22180)”. 15 pockets (best druggability 0.80). MolNFT v1 #303164 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22180
- Type
- protein
- Length
- 956 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1392B753cF15F20A431316F678bC32DC3F16C559
- Molecule
- Plasma membrane ATPase 1
- UniProt
- P22180
- Pockets
- 15 · best druggability 0.80
Structure
1 distinct chain · 54% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plasma membrane ATPase 1 | protein | 956 | 54% helix, 13% strand | P22180 |
Pockets
15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.80 | 0.82 | 72 | empty |
| 2 | 56 | 0.70 | 0.97 | 19 | empty |
| 3 | 526 | 0.62 | 0.75 | 42 | empty |
| 4 | 347 | 0.57 | 0.76 | 33 | empty |
| 5 | 213 | 0.57 | 0.79 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22180
- Elsewhere: UniProt P22180 · AlphaFold DB P22180
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