MolNFT v1 · #303013 · protein
AlphaFold monomer V2.0 prediction for plexin-B2 (O15031)
O15031: “AlphaFold monomer V2.0 prediction for plexin-B2 (O15031)”. 20 pockets (best druggability 0.77). MolNFT v1 #303013 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O15031
- Type
- protein
- Length
- 1,838 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Plexin-B2
- UniProt
- O15031
- Pockets
- 20 · best druggability 0.77
Structure
1 distinct chain · 26% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plexin-B2 | protein | 1838 | 26% helix, 32% strand | O15031 |
Pockets
20 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 987 | 0.77 | 0.79 | 69 | empty |
| 2 | 427 | 0.72 | 0.82 | 47 | empty |
| 3 | 415 | 0.57 | 0.74 | 49 | empty |
| 4 | 113 | 0.56 | 0.84 | 21 | empty |
| 5 | 169 | 0.45 | 0.75 | 25 | empty |
Modifications
Observed in the structure: 20 disulfide (disulfide).
Compared structures
- 4E71 · Crystal structure of the rho GTPase binding domain of plexin B2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 4E71 · Crystal structure of the RHO GTPASE binding domain of Plexin B2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15031
- Elsewhere: UniProt O15031 · AlphaFold DB O15031
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