MolNFT v1 · #301546 · protein

AlphaFold monomer V2.0 prediction for calcium-independent phospholipase A2-gamma (D3ZRC4)

D3ZRC4: “AlphaFold monomer V2.0 prediction for calcium-independent phospholipase A2-gamma (D3ZRC4)”. 7 pockets (best druggability 0.75). MolNFT v1 #301546 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: D3ZRC4
Type: protein
Length: 776 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6F7e02049B13f0f0eF041D8589c607F441790c57
Molecule: Calcium-independent phospholipase A2-gamma
UniProt: D3ZRC4
Pockets: 7 · best druggability 0.75

Structure

1 distinct chain · 44% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calcium-independent phospholipase A2-gamma	protein	776	44% helix, 7% strand	D3ZRC4

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	889	0.75	0.79	76	empty
2	292	0.62	0.80	40	empty
3	318	0.52	0.73	40	empty
4	172	0.49	0.77	33	empty
5	158	0.46	0.76	25	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D3ZRC4
Elsewhere: UniProt D3ZRC4 · AlphaFold DB D3ZRC4

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