MolNFT v1 · #301410 · protein
AlphaFold monomer V2.0 prediction for plasminogen (P12545)
P12545: “AlphaFold monomer V2.0 prediction for plasminogen (P12545)”. 8 pockets (best druggability 0.75). MolNFT v1 #301410 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P12545
- Type
- protein
- Length
- 810 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Plasminogen
- UniProt
- P12545
- Pockets
- 8 · best druggability 0.75
Structure
1 distinct chain · 6% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plasminogen | protein | 810 | 6% helix, 24% strand | P12545 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1198 | 0.75 | 0.78 | 120 | empty |
| 2 | 400 | 0.69 | 0.81 | 48 | empty |
| 3 | 661 | 0.63 | 0.74 | 60 | empty |
| 4 | 76 | 0.47 | 0.83 | 22 | empty |
| 5 | 97 | 0.46 | 0.80 | 27 | empty |
Modifications
Observed in the structure: 24 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12545
- Elsewhere: UniProt P12545 · AlphaFold DB P12545
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