MolNFT v1 · #301383 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B4MXR8)
B4MXR8: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B4MXR8)”. 11 pockets (best druggability 0.73). MolNFT v1 #301383 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B4MXR8
- Type
- protein
- Length
- 787 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xE5FC0b4766EbeEdAA6231d28306a4B21e024C6F9
- Molecule
- SERINE/THREONINE-protein kinase PLK4
- UniProt
- B4MXR8
- Pockets
- 11 · best druggability 0.73
Structure
1 distinct chain · 24% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PLK4 | protein | 787 | 24% helix, 19% strand | B4MXR8 |
Pockets
11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 808 | 0.73 | 0.78 | 73 | empty |
| 2 | 535 | 0.61 | 0.74 | 51 | empty |
| 3 | 66 | 0.49 | 0.85 | 25 | empty |
| 4 | 186 | 0.44 | 0.74 | 32 | empty |
| 5 | 187 | 0.43 | 0.73 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4MXR8
- Elsewhere: UniProt B4MXR8 · AlphaFold DB B4MXR8
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