MolNFT v1 · #301380 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B4IAQ8)
B4IAQ8: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B4IAQ8)”. 8 pockets (best druggability 0.70). MolNFT v1 #301380 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B4IAQ8
- Type
- protein
- Length
- 769 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- SERINE/THREONINE-protein kinase PLK4
- UniProt
- B4IAQ8
- Pockets
- 8 · best druggability 0.70
Structure
1 distinct chain · 23% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PLK4 | protein | 769 | 23% helix, 20% strand | B4IAQ8 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1078 | 0.70 | 0.75 | 84 | empty |
| 2 | 133 | 0.65 | 0.87 | 21 | empty |
| 3 | 294 | 0.58 | 0.77 | 39 | empty |
| 4 | 310 | 0.50 | 0.73 | 36 | empty |
| 5 | 110 | 0.42 | 0.77 | 24 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4IAQ8
- Elsewhere: UniProt B4IAQ8 · AlphaFold DB B4IAQ8
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