MolNFT v1 · #301373 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B3M6I4)
B3M6I4: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK4 (B3M6I4)”. 6 pockets (best druggability 0.78). MolNFT v1 #301373 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B3M6I4
- Type
- protein
- Length
- 770 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xEea87110C707BC633005f91030930eEe8cb180B4
- Molecule
- SERINE/THREONINE-protein kinase PLK4
- UniProt
- B3M6I4
- Pockets
- 6 · best druggability 0.78
Structure
1 distinct chain · 23% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PLK4 | protein | 770 | 23% helix, 20% strand | B3M6I4 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.78 | 0.96 | 20 | empty |
| 2 | 907 | 0.68 | 0.74 | 95 | empty |
| 3 | 305 | 0.63 | 0.79 | 49 | empty |
| 4 | 279 | 0.48 | 0.73 | 41 | empty |
| 5 | 123 | 0.38 | 0.74 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B3M6I4
- Elsewhere: UniProt B3M6I4 · AlphaFold DB B3M6I4
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