MolNFT v1 · #301094 · protein
AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol phosphodiesterase (P45723)
P45723: “AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol phosphodiesterase (P45723)”. 1 pocket (best druggability 0.43). MolNFT v1 #301094 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P45723
- Type
- protein
- Length
- 312 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- 1-phosphatidylinositol phosphodiesterase
- UniProt
- P45723
- Pockets
- 1 · best druggability 0.43
Structure
1 distinct chain · 34% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol phosphodiesterase | protein | 312 | 34% helix, 21% strand | P45723 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 117 | 0.43 | 0.77 | 23 | empty |
Compared structures
- 4S3G · Structure of the F249X mutant of phosphatidylinositol-specific phospholipase C from… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4S3G · Structure of the F249X mutant of Phosphatidylinositol-specific phospholipase C from… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4RV3 · Crystal structure of a pentafluoro-Phe incorporated Phosphatidylinositol-specific… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4RV3 · Crystal structure of a pentafluoro-phe incorporated phosphatidylinositol-specific… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I8Y · Structure of the unliganded N254Y/H258Y mutant of the phosphatidylinositol-specific… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I8Y · Structure of the unliganded N254Y/H258Y mutant of the phosphatidylinositol-specific… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I9T · Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I9T · Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I90 · Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I90 · Structure of the N254Y/H258Y mutant of the phosphatidylinositol- specific phospholipase C… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I9J · Structure of the N254Y/H258Y mutant of the phosphatidylinositol- specific phospholipase C… · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4I9J · Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C… · an experimental structure of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45723
- Elsewhere: UniProt P45723 · AlphaFold DB P45723
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