MolNFT v1 · #301029 · protein
AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (Q4R6L3)
Q4R6L3: “AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4…”. 5 pockets (best druggability 0.77). MolNFT v1 #301029 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q4R6L3
- Type
- protein
- Length
- 799 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
- Molecule
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
- UniProt
- Q4R6L3
- Pockets
- 5 · best druggability 0.77
Structure
1 distinct chain · 31% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 | protein | 799 | 31% helix, 23% strand | Q4R6L3 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1013 | 0.77 | 0.79 | 74 | empty |
| 2 | 489 | 0.63 | 0.76 | 54 | empty |
| 3 | 290 | 0.60 | 0.79 | 44 | empty |
| 4 | 210 | 0.58 | 0.80 | 32 | empty |
| 5 | 151 | 0.47 | 0.77 | 31 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4R6L3
- Elsewhere: UniProt Q4R6L3 · AlphaFold DB Q4R6L3
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