MolNFT v1 · #300998 · protein
AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (P10894)
P10894: “AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1…”. 9 pockets (best druggability 0.78). MolNFT v1 #300998 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P10894
- Type
- protein
- Length
- 1,216 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
- UniProt
- P10894
- Pockets
- 9 · best druggability 0.78
Structure
1 distinct chain · 42% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | protein | 1216 | 42% helix, 14% strand | P10894 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 455 | 0.78 | 0.86 | 64 | empty |
| 2 | 1019 | 0.76 | 0.78 | 70 | empty |
| 3 | 374 | 0.73 | 0.84 | 43 | empty |
| 4 | 579 | 0.67 | 0.77 | 62 | empty |
| 5 | 387 | 0.61 | 0.76 | 29 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10894
- Elsewhere: UniProt P10894 · AlphaFold DB P10894
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