MolNFT v1 · #300991 · protein
AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (P32383)
P32383: “AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (P32383)”. 17 pockets (best druggability 0.81). MolNFT v1 #300991 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P32383
- Type
- protein
- Length
- 869 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xee747bB73DB28d63168c8f1FC50610B9a0055D30
- Molecule
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- UniProt
- P32383
- Pockets
- 17 · best druggability 0.81
Structure
1 distinct chain · 34% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 | protein | 869 | 34% helix, 24% strand | P32383 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1189 | 0.81 | 0.83 | 117 | empty |
| 2 | 389 | 0.75 | 0.85 | 40 | empty |
| 3 | 744 | 0.73 | 0.79 | 53 | empty |
| 4 | 58 | 0.72 | 0.98 | 18 | empty |
| 5 | 305 | 0.66 | 0.82 | 40 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32383
- Elsewhere: UniProt P32383 · AlphaFold DB P32383
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