MolNFT v1 · #300989 · protein
AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (O13433)
O13433: “AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (O13433)”. 16 pockets (best druggability 0.77). MolNFT v1 #300989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O13433
- Type
- protein
- Length
- 1,099 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x31C2b8Dda9af930b8C9df8eCc4E387b89CF5fc9A
- Molecule
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- UniProt
- O13433
- Pockets
- 16 · best druggability 0.77
Structure
1 distinct chain · 24% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 | protein | 1099 | 24% helix, 19% strand | O13433 |
Pockets
16 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 394 | 0.77 | 0.87 | 52 | empty |
| 2 | 345 | 0.77 | 0.87 | 50 | empty |
| 3 | 203 | 0.71 | 0.88 | 40 | empty |
| 4 | 176 | 0.68 | 0.86 | 31 | empty |
| 5 | 437 | 0.67 | 0.79 | 49 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O13433
- Elsewhere: UniProt O13433 · AlphaFold DB O13433
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