MolNFT v1 · #300972 · protein
AlphaFold monomer V2.0 prediction for putative phospholipase B-like 2 (Q3TCN2)
Q3TCN2: “AlphaFold monomer V2.0 prediction for putative phospholipase B-like 2 (Q3TCN2)”. 8 pockets (best druggability 0.73). MolNFT v1 #300972 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q3TCN2
- Type
- protein
- Length
- 594 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7782F4817b37743d738e9aF842bf74bd50f2015E
- Molecule
- Putative phospholipase B-like 2
- UniProt
- Q3TCN2
- Pockets
- 8 · best druggability 0.73
Structure
1 distinct chain · 35% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative phospholipase B-like 2 | protein | 594 | 35% helix, 20% strand | Q3TCN2 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 466 | 0.73 | 0.83 | 71 | empty |
| 2 | 78 | 0.43 | 0.80 | 17 | empty |
| 3 | 104 | 0.40 | 0.76 | 22 | empty |
| 4 | 67 | 0.38 | 0.78 | 12 | empty |
| 5 | 87 | 0.38 | 0.77 | 21 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3FGW · One chain form of the 66.3 kDa protein · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 3FGW · One chain form of the 66.3 kda protein · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 3FBX · Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 3FBX · Crystal structure of the lysosomal 66.3 kda protein from mouse solved by S-sad · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 3FGR · Two chain form of the 66.3 kda protein at 1.8 angstroem · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 3FGR · Two chain form of the 66.3 kDa protein at 1.8 Angstroem · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 3FGT · Two chain form of the 66.3 kDa protein from mouse lacking the linker peptide · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 3FGT · Two chain form of the 66.3 kda protein from mouse lacking the linker peptide · an experimental structure of the same protein · chain A against B, TM-score 0.58
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3TCN2
- Elsewhere: UniProt Q3TCN2 · AlphaFold DB Q3TCN2
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