MolNFT v1 · #300818 · protein
AlphaFold monomer V2.0 prediction for secretory phospholipase A2 receptor (P49259)
P49259: “AlphaFold monomer V2.0 prediction for secretory phospholipase A2 receptor (P49259)”. 20 pockets (best druggability 0.79). MolNFT v1 #300818 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49259
- Type
- protein
- Length
- 1,463 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4f93D611eEd0cBE1522504F0c187EE165b1a68c
- Molecule
- Secretory phospholipase A2 receptor
- UniProt
- P49259
- Pockets
- 20 · best druggability 0.79
Structure
1 distinct chain · 17% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Secretory phospholipase A2 receptor | protein | 1463 | 17% helix, 29% strand | P49259 |
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1092 | 0.79 | 0.80 | 76 | empty |
| 2 | 705 | 0.75 | 0.81 | 70 | empty |
| 3 | 864 | 0.71 | 0.76 | 76 | empty |
| 4 | 425 | 0.71 | 0.82 | 56 | empty |
| 5 | 260 | 0.70 | 0.85 | 38 | empty |
Modifications
Observed in the structure: 27 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49259
- Elsewhere: UniProt P49259 · AlphaFold DB P49259
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