MolNFT v1 · #300750 · protein
AlphaFold monomer V2.0 prediction for mycocerosic acid synthase-like polyketide synthase (A0R1E8)
A0R1E8: “AlphaFold monomer V2.0 prediction for mycocerosic acid synthase-like polyketide synthase (A0R1E8)”. 20 pockets (best druggability 0.79). MolNFT v1 #300750 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0R1E8
- Type
- protein
- Length
- 2,111 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x26D3C47A86831ff95e84759c65F671f9744Fa55e
- Molecule
- Mycocerosic acid synthase-like polyketide synthase
- UniProt
- A0R1E8
- Pockets
- 20 · best druggability 0.79
Structure
1 distinct chain · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mycocerosic acid synthase-like polyketide synthase | protein | 2111 | 39% helix, 22% strand | A0R1E8 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 892 | 0.79 | 0.82 | 77 | empty |
| 2 | 602 | 0.75 | 0.82 | 52 | empty |
| 3 | 149 | 0.71 | 0.90 | 29 | empty |
| 4 | 744 | 0.71 | 0.78 | 76 | empty |
| 5 | 326 | 0.70 | 0.83 | 54 | empty |
Compared structures
- 5BP1 · Condensing di-domain (ks-at) of a mycocerosic acid synthase-like (mas- like) pks · an experimental structure of the same protein · chain A against A, TM-score 0.38
- 5BP1 · Condensing di-domain (KS-AT) of a mycocerosic acid synthase-like (MAS-like) PKS · an experimental structure of the same protein · chain A against A, TM-score 0.38
- 5BP2 · Dehydratase domain (dh) of a mycocerosic acid synthase-like (mas-like) pks, crystal form 1 · an experimental structure of the same protein · chain A against B, TM-score 0.13
- 5BP3 · Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 5BP3 · Dehydratase domain (dh) of a mycocerosic acid synthase-like (mas-like) pks, crystal form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.13
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0R1E8
- Elsewhere: UniProt A0R1E8 · AlphaFold DB A0R1E8
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