MolNFT v1 · #300729 · protein

AlphaFold monomer V2.0 prediction for highly reducing polyketide synthase PKS2 (E5AE40)

E5AE40: “AlphaFold monomer V2.0 prediction for highly reducing polyketide synthase PKS2 (E5AE40)”. 20 pockets (best druggability 0.83). MolNFT v1 #300729 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: E5AE40
Type: protein
Length: 2,543 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x24b6633C8ABa741dB6572E7cDdf0Af3176c8A10F
Molecule: Highly reducing polyketide synthase PKS2
UniProt: E5AE40
Pockets: 20 · best druggability 0.83

Structure

1 distinct chain · 39% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Highly reducing polyketide synthase PKS2	protein	2543	39% helix, 22% strand	E5AE40

Pockets

20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	936	0.83	0.84	107	empty
2	979	0.79	0.81	76	empty
3	757	0.79	0.83	71	empty
4	252	0.76	0.89	45	empty
5	482	0.73	0.82	50	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E5AE40
Elsewhere: UniProt E5AE40 · AlphaFold DB E5AE40

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