MolNFT v1 · #300526 · protein
AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family H member 1 (Q80TI1)
Q80TI1 · Pleckstrin homology domain-containing family H member 1: “AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family H member 1 (Q80TI1)”. 11 pockets (best druggability 0.78). MolNFT v1 #300526 on…
- Accession
- Q80TI1
- Type
- protein
- Length
- 1,356 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Pleckstrin homology domain-containing family H member 1
- UniProt
- Q80TI1
- Pockets
- 11 · best druggability 0.78
Structure
1 distinct chain · 35% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pleckstrin homology domain-containing family H member 1 | protein | 1356 | 35% helix, 13% strand | Q80TI1 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 760 | 0.78 | 0.82 | 88 | empty |
| 2 | 518 | 0.67 | 0.78 | 52 | empty |
| 3 | 336 | 0.64 | 0.80 | 47 | empty |
| 4 | 277 | 0.56 | 0.76 | 22 | empty |
| 5 | 225 | 0.54 | 0.77 | 33 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80TI1
- Elsewhere: UniProt Q80TI1 · AlphaFold DB Q80TI1
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