MolNFT v1 · #300450 · protein

AlphaFold monomer V2.0 prediction for polycystin-2 (H2LRU7)

H2LRU7: “AlphaFold monomer V2.0 prediction for polycystin-2 (H2LRU7)”. 9 pockets (best druggability 0.74). MolNFT v1 #300450 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: H2LRU7
Type: protein
Length: 901 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9D5d2d8d9e45c92EDc86241f1A122A30ee3C858c
Molecule: Polycystin-2
UniProt: H2LRU7
Pockets: 9 · best druggability 0.74

Structure

1 distinct chain · 50% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polycystin-2	protein	901	50% helix, 7% strand	H2LRU7

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	235	0.74	0.88	37	empty
2	262	0.58	0.78	34	empty
3	168	0.46	0.76	17	empty
4	152	0.45	0.75	19	empty
5	66	0.34	0.76	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt H2LRU7
Elsewhere: UniProt H2LRU7 · AlphaFold DB H2LRU7

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