MolNFT v1 · #300383 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak-1 (Q17850)

Q17850: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak-1 (Q17850)”. 6 pockets (best druggability 0.79). MolNFT v1 #300383 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q17850
Type: protein
Length: 572 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xEC47C23c8f2f910cE34d11FAfe8cb6877Fef923b
Molecule: SERINE/THREONINE-protein kinase pak-1
UniProt: Q17850
Pockets: 6 · best druggability 0.79

Structure

1 distinct chain · 30% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase pak-1	protein	572	30% helix, 11% strand	Q17850

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1085	0.79	0.80	97	empty
2	59	0.38	0.80	19	empty
3	93	0.30	0.71	17	empty
4	58	0.29	0.75	15	empty
5	56	0.29	0.74	15	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q17850
Elsewhere: UniProt Q17850 · AlphaFold DB Q17850

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