MolNFT v1 · #300379 · protein
AlphaFold monomer V2.0 prediction for polycystic kidney disease protein 1-like 2 (Q7TN88)
Q7TN88: “AlphaFold monomer V2.0 prediction for polycystic kidney disease protein 1-like 2 (Q7TN88)”. 20 pockets (best druggability 0.79). MolNFT v1 #300379 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q7TN88
- Type
- protein
- Length
- 2,461 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- Polycystic kidney disease protein 1-like 2
- UniProt
- Q7TN88
- Pockets
- 20 · best druggability 0.79
Structure
1 distinct chain · 31% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polycystic kidney disease protein 1-like 2 | protein | 2461 | 31% helix, 26% strand | Q7TN88 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1041 | 0.79 | 0.81 | 99 | empty |
| 2 | 967 | 0.75 | 0.78 | 90 | empty |
| 3 | 560 | 0.72 | 0.80 | 72 | empty |
| 4 | 61 | 0.69 | 0.96 | 14 | empty |
| 5 | 395 | 0.65 | 0.78 | 44 | empty |
Modifications
Observed in the structure: 19 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7TN88
- Elsewhere: UniProt Q7TN88 · AlphaFold DB Q7TN88
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