MolNFT v1 · #300344 · protein

AlphaFold monomer V2.0 prediction for protein piwi (Q9VKM1)

Q9VKM1: “AlphaFold monomer V2.0 prediction for protein piwi (Q9VKM1)”. 7 pockets (best druggability 0.78). MolNFT v1 #300344 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9VKM1
Type: protein
Length: 843 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8fCa577425962E967D175b7cf864132866e2F7F9
Molecule: Protein piwi
UniProt: Q9VKM1
Pockets: 7 · best druggability 0.78

Structure

1 distinct chain · 31% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein piwi	protein	843	31% helix, 26% strand	Q9VKM1

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	892	0.78	0.81	90	empty
2	470	0.66	0.78	50	empty
3	408	0.62	0.77	55	empty
4	154	0.46	0.76	25	empty
5	177	0.46	0.75	30	empty

Compared structures

6KR6 · Crystal structure of Drosophila Piwi · an experimental structure of the same protein · chain A against A, TM-score 0.74
6KR6 · Crystal structure of drosophila piwi · an experimental structure of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VKM1
Elsewhere: UniProt Q9VKM1 · AlphaFold DB Q9VKM1

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