MolNFT v1 · #300222 · protein
AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory subunit 5 (Q5ZIB8)
Q5ZIB8: “AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory subunit 5 (Q5ZIB8)”. 10 pockets (best druggability 0.75). MolNFT v1 #300222 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5ZIB8
- Type
- protein
- Length
- 881 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xfEaF74D735fF168EC7797B4e35fC00B610187c3E
- Molecule
- Phosphoinositide 3-kinase regulatory subunit 5
- UniProt
- Q5ZIB8
- Pockets
- 10 · best druggability 0.75
Structure
1 distinct chain · 33% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoinositide 3-kinase regulatory subunit 5 | protein | 881 | 33% helix, 15% strand | Q5ZIB8 |
Pockets
10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 895 | 0.75 | 0.78 | 67 | empty |
| 2 | 605 | 0.72 | 0.80 | 45 | empty |
| 3 | 711 | 0.69 | 0.77 | 53 | empty |
| 4 | 73 | 0.57 | 0.88 | 16 | empty |
| 5 | 420 | 0.55 | 0.73 | 57 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZIB8
- Elsewhere: UniProt Q5ZIB8 · AlphaFold DB Q5ZIB8
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