MolNFT v1 · #300132 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol transfer protein alpha isoform (Q00169)
Q00169: “AlphaFold monomer V2.0 prediction for phosphatidylinositol transfer protein alpha isoform (Q00169)”. 1 pocket (best druggability 0.89). MolNFT v1 #300132 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q00169
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1C9610A440a2df878b14E60F32F675a1820EEd0a
- Molecule
- Phosphatidylinositol transfer protein alpha isoform
- UniProt
- Q00169
- Pockets
- 1 · best druggability 0.89
Structure
1 distinct chain · 34% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol transfer protein alpha isoform | protein | 270 | 34% helix, 28% strand | Q00169 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 771 | 0.89 | 0.92 | 75 | empty |
Compared structures
- 1UW5 · Structure of PITP-alpha complexed to phosphatidylinositol · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 1UW5 · Structure of pitp-alpha complexed to phosphatidylinositol · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 8PQO · PITP in complex with the inhibitor VT01545 · an experimental structure of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00169
- Elsewhere: UniProt Q00169 · AlphaFold DB Q00169
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