MolNFT v1 · #299542 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3-kinase piki-1 (G5EDY0)
G5EDY0: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3-kinase piki-1 (G5EDY0)”. 20 pockets (best druggability 0.85). MolNFT v1 #299542 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- G5EDY0
- Type
- protein
- Length
- 1,607 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Phosphatidylinositol 3-kinase piki-1
- UniProt
- G5EDY0
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 34% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3-kinase piki-1 | protein | 1607 | 34% helix, 17% strand | G5EDY0 |
Pockets
20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 907 | 0.85 | 0.86 | 79 | empty |
| 2 | 1007 | 0.79 | 0.80 | 83 | empty |
| 3 | 955 | 0.77 | 0.80 | 85 | empty |
| 4 | 886 | 0.72 | 0.76 | 74 | empty |
| 5 | 692 | 0.71 | 0.78 | 55 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G5EDY0
- Elsewhere: UniProt G5EDY0 · AlphaFold DB G5EDY0
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